The report of the journal "Journal of Ethnopharmacology" (traditional pharmacy) published in the December 2001 issue of the "Key Laboratory of Virology" in Wuhan University of China pointed out that the "glycoprotein" (GLPG) extracted and purified from mycelium of Ganoderma lucidum The ratio of "sugar" to "protein" is 10.4: 1) that inhibits normal cytopathic disease caused by the first blister virus (HSV-1) and the second herpes virus (HSV-2).
GLPG can also prevent the progress of cell disease, GLPG antiviral effect is proportional to the use of dose, even if the concentration of up to 2000μg / ml, GLPG will not produce toxic cells.
To further understand the GLPG anti-HSV herpes virus activity, the researchers divided the cells into three groups, each in the normal cell virus infection before being infected by the virus, and the virus infection, adding Ganoderma glycoprotein GLPG, together for 48 hours , The results found that for those who have not suffered or just virus infection of cells, GLPG for the protection of cells is more significant.
The mechanism of action of GLPG against blister virus remains to be studied step by step, but from the above experiments, GLPG will make herpes virus can not be adsorbed on normal cells, blister virus and thus no invasion of normal cells for replication work. Obviously, GLPG from Ganoderma lucidum is very suitable for the development of anti-GLPG herpes virus drugs, more valuable is that it is not toxic, will not hurt normal cells.