Modern medical practice has proved that Ganoderma spore powder has a hypotensive effect. For spontaneously hypertensive rats, given Ganoderma lucidum spore powder, can significantly lower blood pressure, while plasma and liver cholesterol levels also decreased. A recent study also found that Ganoderma lucidum polysaccharides can reduce the content of superoxide in the aortic smooth muscle of experimental hypertensive rats and reduce the high levels of oxygen free radicals in the aorta smooth muscle of hypertensive rats to normal levels Of the superoxide dismutase (SOD) activity increased. This shows that Ganoderma lucidum spore powder antioxidant and scavenging the role of oxygen free radicals and its prevention and treatment of hypertension.
It is believed that the antihypertensive effect of Ganoderma lucidum spore powder is mainly related to the triterpenoids contained in it, such as the five triterpenoids derived from 70% methanol extract of Ganoderma lucidum spore powder - ganoderic acid K, S, ganoderal A, ganoderol A and B can inhibit angiotensin converting enzyme. The enzyme activity increased, can cause blood pressure. Therefore, Ganoderma lucidum spore powder contains triterpenoids inhibit angiotensin-converting enzyme activity, and its antihypertensive effect.