Ganoderma lucidum spore powder activated the Phagocytic function of macrophages, glucocorticoid antagonism. Water extract of Ganoderma lucidum spore powder improves peritoneal macrophage in mice of acid phosphatase and "β-glucuronidase activity and hydrogen peroxide content, glucocorticoid hormone on mice's spleen and against DNA synthesis inhibitory effects and the role of fat accumulation in the liver . Mice take spore powder of Ganoderma lucidum on murine peritoneal macrophage Phagocytic function and serum lectin enhancement. Mouse spleen index also increased nonspecific esterase and acid staining. Description of Ganoderma lucidum spore powder enhances the nonspecific immune function, increased cell-mediated immunity and humoral immunity level of g.
Ganoderma lucidum spores powder on D-amino half lactose due to liver damage of protection role: test small rat irrigation stomach (g) and the abdominal injection (p) two species way to drug, alone group small rat liver function ALT activity obviously increased, cell appeared balloon sample swelling and the points-like necrosis, liver damaged serious, by try small rat death rate high, and saline control group has very significantly of differences. D-galactosamine and Ganoderma lucidum spore powder is used compared with saline control group mice had no deaths, half of the liver pathological to normal mice. ALT activity though there are still differences in comparison with the control group, but the Group has significantly reduced (P<0.05). That Spore powder of Ganoderma lucidum on liver injury induced by d-Galactose has the obvious antagonism.
Spore powder of Ganoderma lucidum with significant inhibition of transplanted tumor in mice liver tumors, Sarcoma in mice -180 (S-180) and grid cell Sarcoma in mice (L-II) role. 2-8g/(Kg.d) within the dose range of mice after gavage dosing 7d liver, S-180 and inhibition rate of L-II in 52.2-86.1%,44.9-82.0% and 54%-79.6%, and there is a clear dose-response relationship.  spore powder of Ganoderma lucidum extract has a direct inhibitory effects on the growth of cancer cells in vitro. Spore powder of Ganoderma lucidum extract in 1mg/mL on human cervical carcinoma cell line Hela, human hepatic HepG2 cells, human gastric cancer cell line SGC7901, human leukemia cells HL60 and L1210 murine leukemia cells with strong anti.