Assessment of liver injury
There are many factors, such as hepatitis A, hepatitis B, hepatitis C and other hepatitis virus, or the immune system for the eradication of the virus taken by the attack, or drugs, toxic substances, alcohol, overwork, fat accumulation, Will destroy the liver cells, causing inflammation of the liver.
When the liver cells are destroyed, the two cells in the enzyme, AST (aspartate aminotransferase) and ALT (alanine aminotransferase), will penetrate the blood. So we can blood test the height of these two liver index, the initial level of damage to the liver.
ALT is more important because it is not like AST in muscle and heart tissue also, ALT exists only in the liver, so when it is abnormal in the blood concentration, 100% is the problem of the liver.
Acute liver injury induced by CCl4
In the liver test of Ganoderma lucidum spores oil, the researchers gave 3 healthy mice with low, medium and high dose spore oil, 0.17 g / kg, 0.33 g / kg, 1.00 g / kg per day (0.17 g / kg , 0.33 grams, 1 gram), equivalent to the human body recommended amount of 5 times, 10 times, 30 times.
After 29 days of continuous feeding, the mice were given the chemical toxic substance CCl4 (carbon tetrachloride), induced acute liver injury, and then fed the last spore oil after 4 hours. 24 hours after the detection of blood ALT, ALT, and remove the liver to do pathological analysis.
The experiment was followed by a normal mouse, as well as a model group that gave only CCl4 but did not feed sporozoites. ganoderma supplier