Ganoderma function in the treatment of tumor

- Apr 11, 2017-

The author suggests: how to evaluate the role of Ganoderma lucidum in the treatment of cancer? This is the academic and patients are concerned about the issue. Some of the control clinical report pointed out: Ganoderma lucidum and chemotherapy or radiotherapy combined, can reduce the chemotherapy or radiation therapy caused by bone marrow suppression, gastrointestinal injury and immune function inhibition, improve the quality of life of patients, play a synergistic effect , That is, Ganoderma lucidum can be recommended for adjuvant therapy of cancer.


1) Ganoderma lucidum for the adjuvant treatment of cancer

2) Ganoderma lucidum adjuvant treatment of tumor clinical report

3) Ganoderma lucidum adjuvant therapy of tumor mechanism

4) Chinese medicine is right and evil treatment and Ganoderma lucidum adjuvant treatment of cancer


A) Ganoderma lucidum for the adjuvant treatment of cancer

    Some clinical trials show that Ganoderma lucidum and chemotherapy or radiation therapy in combination, for some tumors such as esophageal cancer, gastric cancer, colorectal cancer, lung cancer, liver cancer, bladder cancer, kidney cancer, prostate cancer, uterine cancer have a better adjuvant therapy effect.


    The efficacy of the following features: to reduce the radiotherapy and chemotherapy caused by bone marrow suppression such as leukopenia, thrombocytopenia; reduce radiotherapy and chemotherapy caused by gastrointestinal injury such as loss of appetite, nausea, vomiting, etc .; to improve the immune function of cancer patients, enhance the body's anti- Immunity; improve the quality of life of cancer patients, so that the body enhanced. These results show that Ganoderma lucidum can be used as adjuvant therapy for tumor radiotherapy and chemotherapy, play a synergistic effect.


B) Ganoderma lucidum adjuvant treatment of tumor clinical report


    Wang Huaijin and other spores Ganoderma lucidum extract treatment of malignant tumor patients in 22 cases, of which 16 cases of pathological diagnosis, including lung squamous cell carcinoma in 8 cases, 5 cases of invasive breast cancer, small cell lung cancer in 1 case, in line with clinical diagnostic criteria Primary liver cancer in 6 cases. Aged 41-70 years, mean age 60 years old. Difficult 14 cases, female 8 cases. Within 1 month of no top-level chemotherapy and bioremediation modifier treatment. When taking Ganoderma lucidum during the use of other chemicals and traditional Chinese medicine. Patients daily with organic red Ganoderma tablets 50 grams, add water 500ML, boiling for 30 minutes, with organic broken Ganoderma lucidum spore powder 4 grams, sooner or later sub-service, a total of 4 weeks. To the World Health Organization (WHO) standards for evaluation, divided into one of the following criteria:


1) CR (complete remission): visible lesions completely disappeared, more than 4 weeks.

2) PR (partial remission): mass reduction of more than 50%, maintenance time more than 4 weeks.

3) MR (improved or micro): the tumor shrink more than 25%, but less than 50%, no new lesions or cancer metastasis.

4) SD (stable): less than 25% reduction in mass, or increased by no more than 25%, no new lesions or cancer metastasis.

5) PD (progress): mass increased more than 25%, or new lesions appear or cancer metastasis.


    Treatment results can be seen: CR 1 case, PR 2 cases, MR 4 cases, SD 14 cases, PD 1 case. Before and after treatment, the quality of life of Karnofsky patients was improved as follows: 8 cases (36.4%) were higher than those of 10 cases with high quality of life, and 2 cases were lower than 10 cases (9.1%), 7 cases of generalized fatigue symptoms, Accounting for 31.8%. This group of patients did not find nausea, vomiting and other gastrointestinal reactions, also no liver and kidney dysfunction and white blood cells, hemoglobin, platelet decline.


   The authors believe that some patients in this group of patients with tumor treatment is not obvious, because it has grown to a large tumor block is often beyond the cotton dressing 0 level kinetics to kill the range. And after surgery, radiotherapy or chemotherapy after the residual or small metastatic lesions, the above three kinds of treatment is difficult to solve the problem, and immunotherapy may get good results. So Ganoderma lucidum and surgery, radiotherapy and chemotherapy in conjunction with the treatment, in order to produce better anti-tumor effect.


C) Ganoderma lucidum adjuvant treatment of tumor mechanism


    Pharmacological studies have shown that oral or injection of Ganoderma lucidum extract or Ganoderma lucidum polysaccharide and Ganoderma triterpenoids can significantly inhibit a variety of animal inhibition of tumor growth, with significant anti-tumor effect. But the Ganoderma lucidum extract or Ganoderma lucidum polysaccharide directly added to the cultured tumor cells in vitro, can not directly kill the tumor cells. Then Ganoderma lucidum extract or Ganoderma lucidum polysaccharide in vivo anti-tumor effect is how to produce? It has been shown that Ganoderma lucidum polysaccharide can enhance the anti-tumor immune function of the body, such as by enhancing the function of macrophages, natural killer cells (NK) and cytotoxic T cells, indirectly kill tumor cells, but also through macrophages, T lymph Cytokine can inhibit or kill tumor cell cytokines such as tumor necrosis factor (TNF) and interferon (IFN) to kill tumor cells or promote apoptosis. Therefore, the anti-tumor effect of Ganoderma lucidum and its polysaccharide is mainly achieved by enhancing the anti-tumor immunity of the body. Unlike Ganoderma lucidum polysaccharides, the triterpenoids contained in Ganoderma lucidum can inhibit the growth of tumor cells in vitro.


    On the other hand, Ganoderma lucidum can inhibit tumor angiogenesis. When the tumor has just grown around the blood vessels, there must be new blood vessels grow into the tumor tissue inside, the tumor cells can absorb the nutrients needed to grow from the blood, continue to grow or transfer to other places. Pharmacological studies have confirmed that Ganoderma lucidum polysaccharide by inhibiting the proliferation of vascular endothelial cells, and inhibition of tumor angiogenesis, tumor cells lack of blood supply, lack of nutrition, the growth was inhibited.


    Pharmacological studies have also found that Ganoderma lucidum has anti-radiation effects, reduce radiotherapy and chemotherapy drugs caused by gastrointestinal injury, but also enhance the chemical treatment drugs such as cyclophosphamide, doxorubicin, cisplatin, cytarabine and other anti-tumor effect , Which is consistent with the clinical observation of tumor chemotherapy and radiation therapy synergistic attenuated effect is consistent.


4) Chinese medicine is right and evil treatment and Ganoderma lucidum adjuvant treatment of cancer


    Surgical treatment of resectable tumor tissue, chemotherapy and radiotherapy can kill tumor cells by leaving the tumor shrink or disappear, but are not necessarily completely avoid tumor metastasis, may not be able to completely remove the tumor cells. On the contrary, surgery to bring the damage and chemotherapy or radiation therapy toxicity can also reduce the body's anti-tumor immunity, and bone marrow, digestive system, liver, kidney and other vital organs of toxicity, and even directly or indirectly lead to death, This is the saying goes, radiotherapy and chemotherapy, "I am not the same" consequences. According to Chinese medicine treatment, the surgical resection of the tumor, chemotherapy and radiation therapy only pay attention to the "Quxie" while ignoring the "righting", and even hurt the vitality, and thus the purpose of the above treatment does not match the results. Ganoderma lucidum in the tumor chemotherapy and radiotherapy in the role, it is to make up for the lack of the two therapies, that is, to support the righteousness, and truly "righting."