Ganoderma lucidum is one of the important tonic medicines recorded in the history books. Ming Dynasty Li Shizhen in the "Compendium of Materia Medica" records Ganoderma lucidum can be "Jiufu light body is not old, longevity immortal", its efficacy, including diuretic, blood, detoxification, strong liver, intestines, strong heart, blood pressure, cold , Anti-inflammatory, immune and so on. In accordance with the "Shen Nong's Herbal Classic", Ganoderma lucidum can be divided into Ganoderma lucidum, black Chi, Qingzhi, white Chi, Huang Zhi and purple six. Which Qingzhi (also known as Longzhi) with liver qi, black Chi (also known as Hyun Chi) can enhance renal function, Huang Zhi (also known as Jinzhi) is dominate the heart disease. Through the preliminary study of modern science, shows that Ganoderma is still anti-tumor and stimulate immune function and other important functions. Analysis of HPLC (high pressure liquid chromatography) showed that Ganoderma lucidum contains a variety of special compounds, including Adenosine, polysaccharide, three posts, protein and organic germanium, its physiological function is worth further study.
With the development of business and society, living standards are increasing, the demand for various kinds of alcohol also increased. Although the amount of alcohol on the physical and mental are beneficial, but the excessive drinking caused by drunken discomfort, and even serious alcoholism is a threat to the health and life of modern people. Therefore, countries around the world to reduce drunken discomfort and other drugs or healthy food development are extremely high demand and the vast majority of the market.
In recent years, the domestic market on the solution of liquor products to protect the long God (Japan Kato Club and Taiwan Longxing Chemical Company) and the grape king of the best solution of the best solution. In Japan, the market is about more than 100 kinds of various types of hangover marketing, showing that its market demand and the vigorous development of research and development work. However, the analysis of the current variety of vitamins, minerals and so-called liver function to promote substances. Although it has the effect of reducing the physical discomfort of the drink (it is said that there are three to five percent of the effect), but there is no direct ability to break down alcohol. In other words, the main function of these products is to enhance the liver function or make the liver overload work so that the body feel a little comfortable.
Obviously, long-term use of such products may be the side effects of the user mistakenly believe that can be no fear of drinking, and unknowingly more by the harm of alcohol. The target product of this research program is to improve the existing products, so that it has a direct decomposition of alcohol, significantly reduce the probability of alcohol into the body, and to prevent alcohol on the human body further harm, can be described as a dual purpose.
The purpose of this study is to explore the efficacy of Ganoderma lucidum to promote liver function and hangover. The results will not only contribute to the development of hangover products, but even the future for the treatment of alcoholism potential. The goal of the first year of the program is to analyze the ability of decomposing alcohol in Ganoderma lucidum constituents and to develop recipes to develop preliminary products with hangover and enhance liver function. The second year of the goal is to genetic engineering method to separate the alcohol alcohol decomposition of the gene, and protein engineering technology to improve its stability to the acid to significantly improve the decomposition of Ganoderma lucidum alcohol decomposition products.